Back to Search
Start Over
Cu/graphene oxide composited coatings for preventing clinical implant bacterial infections: an antibacterial mechanism study.
- Source :
-
Digest Journal of Nanomaterials & Biostructures (DJNB) . Apr-Jun2023, Vol. 18 Issue 2, p657-668. 12p. - Publication Year :
- 2023
-
Abstract
- Recently, graphene oxide (GO) based materials have shown great potential in the treatment of implant bacterial infections due to its inherent antibacterial activity. However, the effect of GO-based materials on biological systems particularly the antibacterial mechanisms is still not clear. In this study, GO, NaBH4 treated GO (GO-Y), copper decorated GO (GO-Cu, GO-Cu-GO) composited coatings were prepared on the surface of silicon dioxide (SiO2) substrate by spin-coating and chemical in-situ formation. The growth of Escherichia coli (E. coli) and Staphylococcus aureus (S. aureus) on GO-Y, GO-Cu, and GO-Cu-GO were significantly inhibited, especially on GO-Cu and GO-Cu-GO coatings. The implied antibacterial mechanism of GO-Cu-Cu coatings was further studied and discussed. The enhanced antibacterial performance of GO-Cu-GO coatings has significant potential application in preventing clinical implant bacterial infections. Moreover, the systematic study of various antibacterial effects also enriches our knowledge of the possible antibacterial mechanisms of graphene-based materials. [ABSTRACT FROM AUTHOR]
- Subjects :
- *GRAPHENE oxide
*BACTERIAL diseases
*OXIDE coating
*COPPER
*ESCHERICHIA coli
Subjects
Details
- Language :
- English
- ISSN :
- 18423582
- Volume :
- 18
- Issue :
- 2
- Database :
- Academic Search Index
- Journal :
- Digest Journal of Nanomaterials & Biostructures (DJNB)
- Publication Type :
- Academic Journal
- Accession number :
- 164897533
- Full Text :
- https://doi.org/10.15251/DJNB.2023.182.657