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Change with exercise in QT dispersion in infarct-related myocardium after angioplasty
- Source :
-
International Journal of Cardiology . Mar2005, Vol. 99 Issue 1, p105-110. 6p. - Publication Year :
- 2005
-
Abstract
- Background: The aim of this study was to evaluate the relationship between exercise-induced QT dispersion and condition of infarct-related myocardium including myocardial scar after angioplasty assessed with exercise perfusion single photon emission computed tomography (SPECT). Methods: Exercise thallium-201 SPECT was performed 6 months after successful direct angioplasty in 67 male patients (60.6±11.5 years), who had Q wave infarction resulting from single vessel disease, and the number of perfusion defect areas (DS) was measured at rest and exercise together with QT (QTc) dispersion. Results: In 52 patients with resting perfusion defects, the exercise-induced change in DS was correlated to the change in QT (or QTc) dispersion (r=-0.51 or r=-0.531, p<0.0001). When the patients were grouped according to the patterns of transient perfusion defect, there were significant differences in ΔQT dispersion and ΔQTc dispersion among infarct-related three groups (reverse, fixed, and partial redistributions) and normal volunteers (ΔQT dispersion; -5.7±12.7 ms in 13 patients with reverse redistribution, -16.3±13.1 ms in 30 patients with fixed redistribution, -28.9±29.5 ms in 9 patients with partial redistribution, and +3.4±20.9 ms in 12 normal volunteers, p=0.0098; ΔQTc dispersion; +18.2±20.8 ms, +1.4±16.7 ms, -15.4±30 ms, and +19±27.5 ms, p=0.0017, respectively). ΔQTc dispersion estimated the SPECT image patterns (p=0.0002) with a sensitivity of 67.3%, a specificity of 83.7% and an accuracy of 78.2%. Conclusions: The change with exercise in QT dispersion may help detect the condition of infarct-related myocardium after angioplasty. [Copyright &y& Elsevier]
- Subjects :
- *CARDIOMYOPATHIES
*MYOCARDIAL infarction
*ANGIOPLASTY
*VASCULAR surgery
Subjects
Details
- Language :
- English
- ISSN :
- 01675273
- Volume :
- 99
- Issue :
- 1
- Database :
- Academic Search Index
- Journal :
- International Journal of Cardiology
- Publication Type :
- Academic Journal
- Accession number :
- 16512124
- Full Text :
- https://doi.org/10.1016/j.ijcard.2003.12.029