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Gold catalyzed hydrofluorination of propargyl alcohols promoted by fluorine-hydrogen bonding.

Authors :
Yang, Hui
Wang, Shaowen
Wang, Jie
Xu, Xiangsheng
Li, Xiaoqing
Source :
Chemical Communications. 7/28/2023, Vol. 59 Issue 59, p9078-9081. 4p.
Publication Year :
2023

Abstract

The hydroxyl group was discovered to promote gold catalyzed hydrofluorination of alkynes via hydrogen bonding interaction. Based on this strategy, propargyl alcohols could be hydrofluorinated smoothly using Et3N·3HF under acidic additive-free conditions, which provided a straightforward alternative protocol for the synthesis of 3-fluoroallyl alcohols. [ABSTRACT FROM AUTHOR]

Details

Language :
English
ISSN :
13597345
Volume :
59
Issue :
59
Database :
Academic Search Index
Journal :
Chemical Communications
Publication Type :
Academic Journal
Accession number :
165130233
Full Text :
https://doi.org/10.1039/d3cc02275g