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Regional and time course differences in sweat cortisol, glucose, and select cytokine concentrations during exercise.
- Source :
-
European Journal of Applied Physiology . Aug2023, Vol. 123 Issue 8, p1727-1738. 12p. - Publication Year :
- 2023
-
Abstract
- Introduction: The use of sweat as a biofluid for non-invasive sampling and diagnostics is a popular area of research. However, concentrations of cortisol, glucose, and cytokines have not been described across anatomical regions or as time progresses throughout exercise. Purpose: To determine regional and time course differences in sweat cortisol, glucose, and select cytokines (EGF, IFN-γ, IL-1β, IL-1α, IL-1ra, TNF-α, IL-6, IL-8, and IL-10). Methods: Sweat was collected with absorbent patches from eight subjects (24–44 y; 80.2 ± 10.2 kg) on the forehead (FH), right dorsal forearm (RDF), right scapula (RS), and right triceps (RT) at 0–25 min, 30–55 min, and 60–85 min during 90 min of cycling (~ 82% HRmax) in a heated chamber (32 °C, 50% rh). ANOVA was used to determine the effect of site and time on outcomes. Data are reported as LS means ± SE. Results: There was a significant effect of location on sweat analyte concentrations with FH having higher values than most other regions for cortisol (FH: 1.15 ± 0.08 ng/mL > RDF: 0.62 ± 0.09 ng/mL and RT: 0.65 ± 0.12 ng/mL, P = 0.02), IL-1ra (P < 0.0001), and IL-8 (P < 0.0001), but lower concentrations for glucose (P = 0.01), IL-1α (P < 0.0001), and IL-10 (P = 0.02). Sweat IL-1β concentration was higher on the RS than RT (P < 0.0001). Sweat cortisol concentration increased (25 min: 0.34 ± 0.10 ng/mL < 55 min: 0.89 ± 0.07 ng/mL < 85 min: 1.27 ± 0.07 ng/mL; P < 0.0001), while EGF (P < 0.0001), IL-1ra (P < 0.0001), and IL-6 (P = 0.02) concentrations decreased over time. Conclusion: Sweat analyte concentrations varied with time of sampling and anatomical region, which is essential information to consider when conducting future work in this area. Clinical trial identifier: NCT04240951 registered January 27, 2020. [ABSTRACT FROM AUTHOR]
- Subjects :
- *HYDROCORTISONE
*GLUCOSE
*CYTOKINES
*INTERLEUKIN-10
*INTERLEUKIN-6
Subjects
Details
- Language :
- English
- ISSN :
- 14396319
- Volume :
- 123
- Issue :
- 8
- Database :
- Academic Search Index
- Journal :
- European Journal of Applied Physiology
- Publication Type :
- Academic Journal
- Accession number :
- 165466826
- Full Text :
- https://doi.org/10.1007/s00421-023-05187-3