基于 434 221 张处方数据探讨儿科常用中成药 适应证审核及其规则的建立.

OBJECTIVE: To investigate the current status of clinical use of Chinese patent medicines in pediatrics through the indication review of Chinese patent medicines in pediatric outpatient and emergency departments in 13 medical institutions, and to put forward relevant countermeasures and suggestions for the existing problems. METHODS: Retrospective analysis method was used to collect the prescriptions of Chinese patent medicines in pediatric outpatient and emergency departments of 13 medical institutions from Oct. to Dec. 2019. The rational prescription, controversial prescription and irrational prescription were judged in terms of indications, and the results of each judgment and the priority of the specific varieties in the use problem were statistically analyzed. RESULTS: Among the 434 221 Chinese patent medicine prescriptions, 284 257 (65. 46%) were rational prescriptions in terms of indications, 130 238 (29. 99%) were controversial prescriptions, and 19 726 (4. 54%) were irrational prescriptions. Among them, the most controversial prescription was the antipyretic agent, and the most controversial prescription was the use of Xiao’ er Chiqiao Qingre granules. Most of the irrational prescriptions were supplement and supporting agents, yet Lingyangjiao capsule was the most irrational. CONCLUSIONS: According to the investigation, there are some controversial problems in the clinical use of commonly used Chinese patent medicines in pediatrics, which can be further studied by Delphi method by making expert questionnaire, so as to establish the corresponding prescription review rules. [ABSTRACT FROM AUTHOR]