CD36 调控脂质代谢作用及机制.

Lipid metabolism is an important metabolic process of the body, and its disorder will lead to many diseases. Cluster of differentiation 36 (CD36) is a scavenger receptor highly expressed in monocytes, macrophages, smooth muscle cells and adipocytes. It is the main receptor and transporter for the recognition of oxidized low-density lipoprotein or long-chain fatty acids. So it plays an important role in the process of lipid metabolism. The review recapitulates the update and current advances on the structure and function of CD36 gene and protein, expounds the role of CD36 in the process of lipid metabolism, and systematically summarizes the molecular mechanism that CD36 cascade AMPK, mTOR and MAPK signaling pathways to participate in the process of lipid metabolism, providing a theoretical basis for the relevant biological research. [ABSTRACT FROM AUTHOR]