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Droplet-Based Microfluidics: Applications in Pharmaceuticals.

Authors :
Trinh, Thi Ngoc Diep
Do, Hoang Dang Khoa
Nam, Nguyen Nhat
Dan, Thach Thi
Trinh, Kieu The Loan
Lee, Nae Yoon
Source :
Pharmaceuticals (14248247). Jul2023, Vol. 16 Issue 7, p937. 22p.
Publication Year :
2023

Abstract

Droplet-based microfluidics offer great opportunities for applications in various fields, such as diagnostics, food sciences, and drug discovery. A droplet provides an isolated environment for performing a single reaction within a microscale-volume sample, allowing for a fast reaction with a high sensitivity, high throughput, and low risk of cross-contamination. Owing to several remarkable features, droplet-based microfluidic techniques have been intensively studied. In this review, we discuss the impact of droplet microfluidics, particularly focusing on drug screening and development. In addition, we surveyed various methods of device fabrication and droplet generation/manipulation. We further highlight some promising studies covering drug synthesis and delivery that were updated within the last 5 years. This review provides researchers with a quick guide that includes the most up-to-date and relevant information on the latest scientific findings on the development of droplet-based microfluidics in the pharmaceutical field. [ABSTRACT FROM AUTHOR]

Details

Language :
English
ISSN :
14248247
Volume :
16
Issue :
7
Database :
Academic Search Index
Journal :
Pharmaceuticals (14248247)
Publication Type :
Academic Journal
Accession number :
169325053
Full Text :
https://doi.org/10.3390/ph16070937