CLINICAL PROFILE, ANGIOGRAPHIC PROFILE AND OUTCOME IN ACUTE CORONARY SYNDROME PATIENTS IN A TERTIARY CARE HOSPITAL.

Objective: To represents the demographic profile, clinical characteristics, frequency of risk factors and distribution of lesions and findings on coronary angiogram in acute coronary syndrome (ACS) patients. Methodology: This retrospective cross sectional study was conducted from January 2020 to December 2021 at the Department of Cardiology, Lady Reading Hospital, Peshawar. Clinical profile, risk factors and angiographic finding were collected from the history ans medical record of patients and entered on proforma. The study comprised of all patients presenting with ACS to tertiary care set up. Inclusion criteria was patients presenting with chest pain suggestive of angina presenting to the ER of the hospital. Results: Of the total 800 patients, 62.50 % were male. Mean age of the study population was 55.58±11.16. Majority had normal BMI. Overall, 33.75% of the patients were smoker. Hypertension was present in 48 % of the patients. Diabetes mellitus and dyslipidemia was observed in 38.8% and 31.2% respectively. Most common presenting complaint was chest pain. Myocardial infarction was observed in 33.25% of the patients. Angiographic distribution of lesion showed that 20.38% had SVCAD. About 30% had DVCAD and 27.50% had TVCAD. On the other hand, 22.25% patient had normal coronary vessel. PCI was performed in 350(43.75%) of the patients where CABG was recommended in 16.13%. Right dominance was observed in 705(88.12%) of the individuals. Conclusion: Single vessel coronary artery disease is the most common finding and most common treatment option is PCI. Hypertension and smoking were the most common risk factors in patients presenting as ACS. [ABSTRACT FROM AUTHOR]