Back to Search
Start Over
Amidyl Radical Directed γ‐C(sp3)−H Functionalization with Silyl Enol Ethers via Photoredox Catalysis.
- Source :
-
European Journal of Organic Chemistry . 8/14/2023, Vol. 26 Issue 31, p1-5. 5p. - Publication Year :
- 2023
-
Abstract
- Herein we reported an efficient photoredox‐catalyzed reaction for site‐selective C(sp3)−H functionalization of carboxamides with silyl enol ethers as radical acceptors. The reaction proceeded through amidyl radical‐directed 1,5‐hydrogen atom transfer (1,5‐HAT) and C(sp3)−C(sp3) bond formation via radical addition of silyl enol ethers. The process features mild conditions and high functional‐group tolerance, allowing the preparation of a series of carboxamides with pendant carbonyl moieties. [ABSTRACT FROM AUTHOR]
Details
- Language :
- English
- ISSN :
- 1434193X
- Volume :
- 26
- Issue :
- 31
- Database :
- Academic Search Index
- Journal :
- European Journal of Organic Chemistry
- Publication Type :
- Academic Journal
- Accession number :
- 169943615
- Full Text :
- https://doi.org/10.1002/ejoc.202300543