Neuronal regeneration in the mammalian central nervous system.

Further potential targets are the mechanisms whereby CNS neurons lose regenerative ability as they mature. In the first decades of the 20th century, Ramón y Cajal[1] published observations on the response of neurons to injury, his own and from the work of others. He considered the lack of regeneration in the central nervous system (CNS) to be due to the absence of Schwann cells. [Extracted from the article]