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A water-soluble fluorescent organic nano-photosensitizer for the ratiometric detection of mitochondrial G-quadruplexes with photodynamic therapy potential.

Authors :
Ma, Qing-yu
Li, Xiang
Zhou, Wei
Li, Xia-fen
Liu, Yi-chen
Feng, Gai-li
Tan, Hongwei
Zhang, Yuan
Xing, Guo-wen
Source :
Chemical Communications. 9/4/2023, Vol. 59 Issue 68, p10287-10290. 4p.
Publication Year :
2023

Abstract

We report a water-soluble AIEgen (TPAL) that can self-assemble into fluorescent organic nanoparticles for the ratiometric detection of mitochondrial DNA (mtDNA) parallel G-quadruplexes (G4s) with high selectivity, a low detection limit and photodynamic therapy (PDT) potential. [ABSTRACT FROM AUTHOR]

Details

Language :
English
ISSN :
13597345
Volume :
59
Issue :
68
Database :
Academic Search Index
Journal :
Chemical Communications
Publication Type :
Academic Journal
Accession number :
170062079
Full Text :
https://doi.org/10.1039/d3cc02788k