Cyclin D2-positive mantle cell lymphoma with t(2;12)(p12;p13) arising in immune deficiency/dysregulation.

Since the BAFF receptor is expressed in most cases of MCL [[12]], B cell abnormalities in RA might have triggered and exacerbated the cyclin D2-positive MCL in our case. A cervical lymph node biopsy showed a nodular growth pattern and a dense infiltrate of medium-sized monomorphic atypical lymphoid cells with a low MIB-1 index (40%). [Extracted from the article]