Highly sensitive fiber SPR sensor based on InSe nanosheets.

• The introduction of InSe nanosheets significantly improves the sensitivity and stability of optical fiber SPR sensors. • The introduction of InSe nanosheets improves the FOM of the sensor. • The sensor film was coated by layer-by-layer self-assembly method. • The superiority of InSe in optical fiber SPR sensor is revealed and compared with traditional sensitization methods. • This paper provides a new direction for the further development and application of optical fiber SPR sensors in related fields. Surface plasmon resonance (SPR) optical fiber sensors exhibit advantages such as small size, immunity to electromagnetic interference, and corrosion resistance, and are currently widely applied in the field of biodetection. However, their sensitivity and reusability are still limited in detecting biomolecules, trace concentrations, and weak signals. This paper proposes an approach by utilizing indium selenide (InSe) nanoflakes to enhance the surface electric field strength of the metal layer. InSe is a two-dimensional material that exhibits higher charge carrier mobility and refractive index compared to traditional two-dimensional materials, thereby promoting electron transfer and inducing a larger SPR effect. By testing the sensors composed of InSe nanosheets with different thicknesses, it is found that the sensitivity of InSe nanosheets with a thickness of 40 nm is up to 4655.76 nm/RIU, which is much higher than the sensitivity of traditional Au film sensors and 52 % higher than that of MoS 2 -Au film SPR sensors with the same structure. Moreover, the sensor has a higher FOM value of 33.25 RIU−1 and shows excellent characteristics in repeatability and stability experiments. In this paper, a new method is proposed to enhance the sensitivity of SPR sensors and realize the monitoring of lower biomolecule concentration and weak signal. In addition, the great potential of indium selenide nanosheets in optical applications is emphasized. [ABSTRACT FROM AUTHOR]