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CD8 T Cell‐Derived Exosomal miR‐186‐5p Elicits Renal Inflammation via Activating Tubular TLR7/8 Signal Axis (Adv. Sci. 25/2023).
- Source :
-
Advanced Science . 9/5/2023, Vol. 10 Issue 25, p1-1. 1p. - Publication Year :
- 2023
-
Abstract
- In specific, miR-186-5p is enriched in exosomes of activated CD8 T cells and preferentially enters renal tubular cells where it directly binds endosomal TLR7/8 and initiates renal inflammation. CD8 T Cell-Derived Exosomal miR-186-5p Elicits Renal Inflammation via Activating Tubular TLR7/8 Signal Axis (Adv. Sci. 25/2023) In article number 2301492, Ke Zen, Zhihong Liu, and co-workers identify exosomal miR-186-5p from activated CD8 T cells as such circulating pathogenic factor that causes renal dysfunction. [Extracted from the article]
- Subjects :
- *CD8 antigen
*INFLAMMATION
*T cells
Subjects
Details
- Language :
- English
- ISSN :
- 21983844
- Volume :
- 10
- Issue :
- 25
- Database :
- Academic Search Index
- Journal :
- Advanced Science
- Publication Type :
- Academic Journal
- Accession number :
- 171385679
- Full Text :
- https://doi.org/10.1002/advs.202370171