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Synthesis of 5-oxo-1-(5-R-1,3,4-thiadiazol-2-yl)pyrrolidine-3-carboxylic acids.
- Source :
-
Russian Chemical Bulletin . Aug2023, Vol. 72 Issue 8, p1837-1843. 7p. - Publication Year :
- 2023
-
Abstract
- A series of new heterocyclic ensembles, derivatives of 5-oxo-1-(1,3,4-thiadiazol-2-yl)-pyrrolidine-3-carboxylic acid, was synthesized by heating 5-substituted 1,3,4-thiadiazol-2-amines and itaconic acid under solvent-free conditions or with the addition of acetic acid at 140–150 °C. The resulting acids can be used as building blocks in the synthesis of new potentially biologically active heterocyclic compounds. [ABSTRACT FROM AUTHOR]
- Subjects :
- *ITACONIC acid
*BIOACTIVE compounds
*THIADIAZOLES
*ACIDS
*ACETIC acid
Subjects
Details
- Language :
- English
- ISSN :
- 10665285
- Volume :
- 72
- Issue :
- 8
- Database :
- Academic Search Index
- Journal :
- Russian Chemical Bulletin
- Publication Type :
- Academic Journal
- Accession number :
- 171386959
- Full Text :
- https://doi.org/10.1007/s11172-023-3966-z