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A cyanine derivative-based NIR fluorescent probe for hydrogen sulfide bioimaging and food spoilage monitoring.
- Source :
-
Dyes & Pigments . Nov2023, Vol. 219, pN.PAG-N.PAG. 1p. - Publication Year :
- 2023
-
Abstract
- Hydrogen sulfide (H 2 S) is a vital gas signaling molecule that performs crucial physiological functions in biological systems, and it can also cause food safety problems. In this study, we developed a cyanine derivative-based mitochondrial-targeted near-infrared fluorescent probe PC-H 2 S for detecting H 2 S. When PC-H 2 S reacted with H 2 S, it reached maximum fluorescence intensity at 656 nm and detection limit as low as 34 nM, and exhibited strong chromogenic response from green to red for H 2 S. Moreover, PC-H 2 S could be utilized to identify H 2 S generated during food spoilage and thus monitored the process of food spoilage. More significantly, PC-H 2 S showed excellent mitochondrial targeting capabilities and endogenous/exogenous H 2 S imaging of living cells and zebrafish could be performed. As a result, this research provides an attractive method for detecting H 2 S in food and biological systems and has potential value in physiopathological research. [Display omitted] • A cyanine derivative-based mitochondrial-targeted NIR fluorescent probe PC-H 2 S for detecting H 2 S was developed. • PC-H 2 S had a low detection limit and exhibited strong chromogenic response from green to red for H 2 S in naked eyes and UV light. • PC-H 2 S test strips was capable of monitoring H 2 S produced by food spoilage. • PC-H 2 S could be used for living cells and zebrafish imaging. [ABSTRACT FROM AUTHOR]
Details
- Language :
- English
- ISSN :
- 01437208
- Volume :
- 219
- Database :
- Academic Search Index
- Journal :
- Dyes & Pigments
- Publication Type :
- Academic Journal
- Accession number :
- 171392846
- Full Text :
- https://doi.org/10.1016/j.dyepig.2023.111644