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Synthesis and antituberculosis action of symmetric acridin-9-yl-bis-benzothiazol- 2-yl-amines.
- Source :
-
Indian Journal of Chemistry (0019-5103) . Jul2023, Vol. 62 Issue 7, p691-695. 5p. - Publication Year :
- 2023
-
Abstract
- A new series of symmetric acridin-9-yl-bis-benzothiazol-2-yl-amines have been synthesized in good to excellent yields by intra-molecular cyclization of 1-acridin-9-yl-1-benzothiazol-2-yl-3-aryl thiourea and screened for their in vitro antitubercular activity against Mycobacterium tuberculosis by BACTEC radiometric method. The synthesis of new analogues bearing an acridine-linked chloro-substituted benzothiazole has demonstrated enhanced antituberculosis activity. [ABSTRACT FROM AUTHOR]
Details
- Language :
- English
- ISSN :
- 00195103
- Volume :
- 62
- Issue :
- 7
- Database :
- Academic Search Index
- Journal :
- Indian Journal of Chemistry (0019-5103)
- Publication Type :
- Academic Journal
- Accession number :
- 171872407
- Full Text :
- https://doi.org/10.56042/ijc.v62i7.430