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Maternal and fetal outcomes in pregnant patients with non-cirrhotic portal hypertension: A systematic review and meta-analysis.
- Source :
-
Obstetric Medicine (1753-495X) . Sep2023, Vol. 16 Issue 3, p170-177. 8p. - Publication Year :
- 2023
-
Abstract
- Background: Concerned studies with respect to the outcome of pregnant patients with non-cirrhotic portal hypertension are limited. Thus, a systematic review and meta-analysis of the available literature was conducted. Methods: A literature search was conducted from 1999 to December 2021 for studies evaluating pregnancy outcomes in patients with non-cirrhotic portal hypertension. Results: Twelve studies were included in the meta-analysis. The pooled rate of variceal bleeding, ascites and severe anemia requiring blood transfusion were 9.6%, 2.3%, and 14.9%, respectively. The pooled rate of spontaneous miscarriage, gestational hypertension, delivery by cesarean section, and postpartum hemorrhage were 11.9%, 4.5%, 36.7%, and 4.7%, respectively. The pooled stillbirth rate was 2.5% and among the live births, the pooled rates of preterm birth, low birth weight, intensive care unit admission, and neonatal mortality were 21.6%, 18.7%, 15.5%, and 1.8%, respectively. Conclusion: Pregnancy in patients with non-cirrhotic portal hypertension is associated with increased maternal & fetal morbidity but mortality remains low. [ABSTRACT FROM AUTHOR]
Details
- Language :
- English
- ISSN :
- 1753495X
- Volume :
- 16
- Issue :
- 3
- Database :
- Academic Search Index
- Journal :
- Obstetric Medicine (1753-495X)
- Publication Type :
- Academic Journal
- Accession number :
- 171988736
- Full Text :
- https://doi.org/10.1177/1753495X221143864