Bidirectional regulation of tumor associated neutrophils and their role in urothelial bladder cancer : a literature review.

Urothelial bladder cancer (UBC) is one of the most common malignant tumors in urology, and its occurrence and progression are closely related to the tumor microenvironment (TME). Tumor-associated neutrophils (TAN), as an important type of immune cells in TME, have been proven to have anti-tumor or pro-tumor regulatory effects on various tumors, which are related to their heterogeneity and plasticity. The study on TAN' s bidirectional regulation may provide new targets for tumor treatment. This article reviews the current status of TAN ' s bidirectional regulation research by searching recent literature, and summarizes its research progress in UBC. [ABSTRACT FROM AUTHOR]