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PD-L1 and CD58 co-regulated by CMTM6 play yin and yang to shape anti-tumor immunity.
- Source :
-
Cancer Cell . Oct2023, Vol. 41 Issue 10, p1701-1704. 4p. - Publication Year :
- 2023
-
Abstract
- The CD58-CD2 axis regulates T cell-mediated cancer immunity, but little is known about the regulation of CD58. In two recent papers pubished in Cancer Cell , Miao et al. and Ho et al. define a mechanism of CD58 regulation by CMTM6 and show an unexpected yin-yang link between PD-L1 and CD58. The CD58-CD2 axis regulates T cell-mediated cancer immunity, but little is known about the regulation of CD58. In two recent papers published in Cancer Cell , Miao et al. and Ho et al. define a mechanism of CD58 regulation by CMTM6 and show an unexpected yin-yang link between PD-L1 and CD58. [ABSTRACT FROM AUTHOR]
- Subjects :
- *PROGRAMMED death-ligand 1
*CELLULAR immunity
*IMMUNITY
*CANCER cells
*T cells
Subjects
Details
- Language :
- English
- ISSN :
- 15356108
- Volume :
- 41
- Issue :
- 10
- Database :
- Academic Search Index
- Journal :
- Cancer Cell
- Publication Type :
- Academic Journal
- Accession number :
- 172778601
- Full Text :
- https://doi.org/10.1016/j.ccell.2023.08.009