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Stem-Cell Aging and Pathways to Precancer Evolution.
- Source :
-
New England Journal of Medicine . 10/5/2023, Vol. 389 Issue 14, p1310-1319. 10p. - Publication Year :
- 2023
-
Abstract
- The article focuses on the relationship between stem cell aging and the development of precancerous conditions. Topics discussed include the role of specific mutations and epigenetic changes in initiating precancerous stem cell expansion, the impact of chronic inflammation on stem cell aging, and the progression of precancer stem cells into self-renewing malignant stem cells.
Details
- Language :
- English
- ISSN :
- 00284793
- Volume :
- 389
- Issue :
- 14
- Database :
- Academic Search Index
- Journal :
- New England Journal of Medicine
- Publication Type :
- Academic Journal
- Accession number :
- 172795211
- Full Text :
- https://doi.org/10.1056/NEJMra2304431