Secondary membranous nephropathy associated to autoimmune polyglandular syndrome Type II.

While infections, drugs, tumors, and autoimmune diseases such as SLE are known to cause secondary membranous nephropathy, there are limited reports of Graves' disease causing secondary membranous nephropathy. Our patient's development of several autoimmune disorders and endocrinopathies including Graves' disease, Addison's disease, and hypogonadism, along with membranous nephropathy, supports an underlying autoimmune etiology. However, it remains unclear whether Graves' disease in the setting of APS caused a secondary membranous nephropathy, or whether an antigen antibody process is directly responsible for both our patient's APS and membranous nephropathy. [Extracted from the article]