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Single center experience and literature review of kidney transplantation from non‐ideal donors with acute kidney injury: Risk and reward.
- Source :
-
Clinical Transplantation . Oct2023, Vol. 37 Issue 10, p1-14. 14p. - Publication Year :
- 2023
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Abstract
- Introduction: There is limited experience transplanting kidneys from either expanded criteria donors (ECD) or donation after circulatory death (DCD) deceased donors with terminal acute kidney injury (AKI). Methods: AKI kidneys were defined by a donor terminal serum creatinine level >2.0 mg/dL whereas non‐ideal deceased donor (NIDD) kidneys were defined as AKI/DCD or AKI/ECDs. Results: From February 2007 to March 2023, we transplanted 266 single AKI donor kidneys including 29 from ECDs, 29 from DCDs (n = 58 NIDDs), and 208 from brain‐dead standard criteria donors (SCDs). Mean donor age (43.7 NIDD vs. 33.5 years SCD), KDPI (66% NIDD vs. 45% SCD), and recipient age (57 NIDD vs. 51 years SCD) were higher in the NIDD group (all p <.01). Mean waiting times (17.8 NIDD vs. 24.2 months SCD) and dialysis duration (34 NIDD vs. 47 months SCD) were shorter in the NIDD group (p <.05). Delayed graft function (DGF, 48%) and 1‐year graft survival (92.7% NIDD vs. 95.9% SCD) was similar in both groups. Five‐year patient and kidney graft survival rates were 82.1% versus 89.9% and 82.1% versus 75.2% (both p = NS) in the NIDD versus SCD groups, respectively. Conclusions: The use of kidneys from AKI donors can be safely liberalized to include selected ECD and DCD donors. [ABSTRACT FROM AUTHOR]
- Subjects :
- *ACUTE kidney failure
*LITERATURE reviews
*KIDNEY transplantation
*GRAFT survival
Subjects
Details
- Language :
- English
- ISSN :
- 09020063
- Volume :
- 37
- Issue :
- 10
- Database :
- Academic Search Index
- Journal :
- Clinical Transplantation
- Publication Type :
- Academic Journal
- Accession number :
- 172894221
- Full Text :
- https://doi.org/10.1111/ctr.15115