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The Clinical Value of the Predicting Bleeding Complications in Patients Undergoing Stent Implantation and Subsequent Dual Antiplatelet Therapy Score in Predicting Long-Term Major Adverse Cardiovascular And Cerebrovascular Events and Major Bleeding in Acute Coronary Syndrome Patients Who Underwent Percutaneous Coronary Intervention
- Source :
-
Angiology . Nov2023, Vol. 74 Issue 10, p958-969. 12p. - Publication Year :
- 2023
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Abstract
- The PRECISE-DAPT (predicting bleeding complications in patients undergoing stent implantation and subsequent dual antiplatelet therapy) score is recommended for predicting out-of-hospital bleeding after percutaneous coronary intervention (PCI). However, its long-term prediction remains unclear. We investigated the performance of this score in predicting long-term outcomes in patients with the acute coronary syndrome (ACS). We divided retrospectively enrolled patients (n = 1071) into two groups according to their PRECISE-DAPT scores: low < 25 and high ≥ 25. Bleeding was assessed using the Bleeding Academic Research Consortium criteria. The ischemic endpoints were all-cause death and major adverse cardiovascular and cerebrovascular events (MACCE). During follow-up (median 7.3 years), MACCE (55 vs 35%, P<.001) and major bleeding (9 vs 4%, P =.002) rates were greater in the high score group. The PRECISE-DAPT score was an independent predictor of MACCE in multivariate analysis (Hazard ratio [HR]: 1.028, 95% confidence interval [CI]: 1.016–1.039, P <.001). Also, the PRECISE-DAPT score predicted all-cause mortality (HR: 2.115, 95% CI: 1.508–2.965, P <.001) at long-term follow-up. The PRECISE-DAPT score may be useful for predicting MACCE at long-term follow-up in addition to the risk of bleeding. [ABSTRACT FROM AUTHOR]
- Subjects :
- *HEMORRHAGE risk factors
*CEREBROVASCULAR disease risk factors
*CAUSES of death
*PERCUTANEOUS coronary intervention
*PREDICTIVE tests
*CONFIDENCE intervals
*MAJOR adverse cardiovascular events
*MULTIVARIATE analysis
*ACUTE coronary syndrome
*SURGICAL complications
*SURGICAL stents
*RETROSPECTIVE studies
*RISK assessment
*TREATMENT effectiveness
*COMPARATIVE studies
*PLATELET aggregation inhibitors
*DESCRIPTIVE statistics
*DISEASE risk factors
Subjects
Details
- Language :
- English
- ISSN :
- 00033197
- Volume :
- 74
- Issue :
- 10
- Database :
- Academic Search Index
- Journal :
- Angiology
- Publication Type :
- Academic Journal
- Accession number :
- 173048140
- Full Text :
- https://doi.org/10.1177/00033197221127073