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Design, synthesis, and evaluation of 1,2,3‐triazole‐based benzenesulfonamide and flavonol hybrid molecules as anticancer agents.
- Source :
-
Journal of the Chinese Chemical Society . Oct2023, Vol. 70 Issue 10, p1924-1936. 13p. - Publication Year :
- 2023
-
Abstract
- Background: The design and synthesis of hybrid molecules will explore finding new drugs. Objectives: The synthesized hybrid molecules to evaluate their biological properties. Methods: Apply click chemistry to tether flavonols and benzenesulfonamide. Results: Two drug candidates show potential against lung cancer. Conclusions: Two drug candidates did not affect the normal cells and provided a new drug design route. [ABSTRACT FROM AUTHOR]
Details
- Language :
- English
- ISSN :
- 00094536
- Volume :
- 70
- Issue :
- 10
- Database :
- Academic Search Index
- Journal :
- Journal of the Chinese Chemical Society
- Publication Type :
- Academic Journal
- Accession number :
- 173054614
- Full Text :
- https://doi.org/10.1002/jccs.202300279