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Laboratory Diagnosis of Tropical Infections.
- Source :
-
Indian Journal of Critical Care Medicine . 2021 Supplement, Vol. 25 Issue S2, pS122-S126. 5p. - Publication Year :
- 2021
-
Abstract
- Highlights: (1) Blood culture is the gold standard for the diagnosis of bacterial infections. (2) Bone marrow culture is more sensitive than blood culture even in patients with enteric fever receiving antibiotics. (3) Microscopic agglutination test is considered the gold standard for diagnosing leptospirosis; however, now IgM ELISA and polymerase chain reaction (PCR) are more frequently used for diagnosis. (4) Tuberculosis is diagnosed with the help of nucleic acid amplification tests like Xpert MTB/RIF Ultra which also detects rifampicin resistance. Other tests include microscopy, Lowenstein-Jensen and mycobacteria growth indicator tube culture, line probe assay. (5) Tropical rickettsial infections are diagnosed by serological reactions (Weil-Felix, ELISA for antibodies) and PCR. (6) For Brucellosis culture from blood, bone marrow or tissue specimens remain the mainstay in diagnosis. (7) Dengue, Zika, Crimean-Congo hemorrhagic fever, Ebola, hantavirus, rabies are diagnosed with reverse transcriptase-polymerase chain reaction. Serological tests like IgM ELISA or paired sera samples for IgG are also used for diagnosis. [ABSTRACT FROM AUTHOR]
- Subjects :
- *DIAGNOSIS of brucellosis
*LEPTOSPIROSIS diagnosis
*BLOOD
*AGGLUTINATION tests
*CELL culture
*DENGUE
*EBOLA virus disease
*MICROSCOPY
*SERODIAGNOSIS
*TROPICAL medicine
*INFECTION
*ENZYME-linked immunosorbent assay
*TUBERCULOSIS
*POLYMERASE chain reaction
*EARLY diagnosis
RICKETTSIAL disease diagnosis
BONE marrow examination
Subjects
Details
- Language :
- English
- ISSN :
- 09725229
- Volume :
- 25
- Issue :
- S2
- Database :
- Academic Search Index
- Journal :
- Indian Journal of Critical Care Medicine
- Publication Type :
- Academic Journal
- Accession number :
- 173333948
- Full Text :
- https://doi.org/10.5005/jp-journals-10071-23813