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Ginsenoside Rg1 attenuates D‐galactose‐induced neural stem cell senescence via the Sirt1‐Nrf2‐BDNF pathway.

Authors :
Hu, Ling
Ran, Jianhua
Wang, Lu
Wu, Mengna
Wang, Ziling
Xiao, Hanxianzhi
Du, Kunhang
Wang, Yaping
Source :
European Journal of Neuroscience. Nov2023, Vol. 58 Issue 9, p4084-4101. 18p.
Publication Year :
2023

Abstract

With the ageing of society's population, neurodegenerative diseases have become an important factor affecting the quality of life and mortality in the elderly. Since its physiopathological processes are complex and the authorized medications have recently been shown to have several adverse effects, the development of safe and efficient medications is urgently needed. In this study, we looked at how ginsenoside Rg1 works to postpone neural stem cell ageing and brain ageing, giving it a solid scientific foundation for use as a therapeutic therapy for neurodegenerative diseases. [ABSTRACT FROM AUTHOR]

Details

Language :
English
ISSN :
0953816X
Volume :
58
Issue :
9
Database :
Academic Search Index
Journal :
European Journal of Neuroscience
Publication Type :
Academic Journal
Accession number :
173469409
Full Text :
https://doi.org/10.1111/ejn.16147