An improved approaches for novel mining serendipitous drug to generate and validate drug repositioning hypotheses from social media comparing with Adaboost algorithm.

The aim of this paper is mining serendipitous drug usage to validate and generate drug repositioning hypotheses from social media. Materials and Methods: Two machine learning algorithms svm with sample size=12 and adaboost algorithm with sample size=12. Results: The support vector machine algorithm has shown more accuracy of (96. 66%) in reducing the false positive rates when compared with Adaboost algorithm accuracy(84.6%). The pre-test was calculated with a g-power value = 80% and threshold 0. 05% confidence interval of 95% mean and standard deviation by using the G-power tool. t is found that the svm algorithm has more accuracy percentage when compared with the Adaboost algorithm. [ABSTRACT FROM AUTHOR]