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Human skin-on-a-chip for mpox pathogenesis studies and preclinical drug evaluation.

Authors :
Zhu, Jia
Abaci, Hasan E.
Source :
Trends in Pharmacological Sciences. Dec2023, Vol. 44 Issue 12, p865-868. 4p.
Publication Year :
2023

Abstract

Timely intervention of preventative and therapeutic measures abated a 2022 mpox global outbreak. However, the high transmissibility and unique pathological characteristics of mpox demand further investigation. Here, we discuss the potentials of human skin-on-a-chip as a valuable model for mpox disease evaluation, to achieve in-depth physiological understanding and desirable therapeutic predictive capabilities. [ABSTRACT FROM AUTHOR]

Subjects

Subjects :
*MONKEYPOX
*PATHOGENESIS

Details

Language :
English
ISSN :
01656147
Volume :
44
Issue :
12
Database :
Academic Search Index
Journal :
Trends in Pharmacological Sciences
Publication Type :
Academic Journal
Accession number :
173702326
Full Text :
https://doi.org/10.1016/j.tips.2023.07.001