Chemical constituents of the leaves of Coriaria nepalensis and their chemotaxonomic significance.

Phytochemical investigation of the leaves of Coriaria nepalensis led to the isolation of fourteen compounds, including five sesquiterpenoids (1 – 5), two oleanane-type triterpenoids (6 , 7), one cycloartane triterpenoid (8), one phytosterol (9), one diterpenoid (10), two α-tocopheroids (11 , 12), and two vitamins (13 , 14). These structures were elucidated on the basis of 1D and 2D NMR spectra (COSY, HSQC, HMBC, and NOESY) and HRESIMS data. To the best of our knowledge, compounds 2 , 3 , 5 , 7 , 8 , 11 , 12 , and 14 are reported from the Coriariaceae family for the first time, and compound 4 was isolated only from the Coriariaceae family. Importantly, compound 1 was identified as a new sesquiterpenoid. Furthermore, chemotaxonomic significance of these isolates was also discussed. • Fourteen compounds, including a new sesquiterpenoid (1), were isolated from the leaves of Coriaria nepalensis. • These compounds include triterpenoids, diterpenoids, sesquiterpenoids, phytosterols, α-tocopheroids, and vitamins. • Compounds 2 , 3 , 5 , 7 , 8 , 11 , 12 , and 14 are reported from the Coriariaceae family for the first time. [ABSTRACT FROM AUTHOR]