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Circulating Tfr/Tfh cell imbalance may contribute to the immunopathogenesis of pemphigus.
- Source :
-
Journal of the European Academy of Dermatology & Venereology . Dec2023, Vol. 37 Issue 12, pe1399-e1402. 4p. - Publication Year :
- 2023
-
Abstract
- This article explores the potential role of an imbalance between two types of immune cells, cTfr and cTfh cells, in the development of pemphigus, a skin disease. The study found that patients with pemphigus had higher levels of cTfh cells and lower levels of cTfr cells compared to healthy individuals. This imbalance was associated with the production of specific antibodies and the severity of the disease. The study suggests that targeting the cTfr/cTfh cell ratio could be a potential treatment approach for pemphigus. [Extracted from the article]
- Subjects :
- *PEMPHIGUS
*SKIN diseases
*ANTIBODY formation
Subjects
Details
- Language :
- English
- ISSN :
- 09269959
- Volume :
- 37
- Issue :
- 12
- Database :
- Academic Search Index
- Journal :
- Journal of the European Academy of Dermatology & Venereology
- Publication Type :
- Academic Journal
- Accession number :
- 173849038
- Full Text :
- https://doi.org/10.1111/jdv.19338