Back to Search
Start Over
Development of a biosensor based on a surface plasmon resonance structure comprising strontium titanate, graphene and affinity layers for malaria diagnosis.
- Source :
-
Modern Physics Letters B . 12/30/2023, Vol. 37 Issue 36, p1-18. 18p. - Publication Year :
- 2023
-
Abstract
- This paper investigates the numerical analysis of a highly performed surface plasmon resonance (SPRE)-based sensor employing a hybrid structure of SrTiO3 (STO) and graphene for rapid detection of malaria. The investigation is performed using the angular interrogation technique and transfer matrix method. The SPRE device has a glass prism, silver (Ag), STO, graphene, affinity layer and sensing medium (SGM). Four coupling prisms are examined and we found the prism N-FK51A corresponds to the highest sensitivity. The sensitivity of the structure N-FK51A/Ag/STO/graphene/affinity layer/SGM is found to be 205.405, 222.222 and 2 5 8. 3 3 3 ∘ /RIU for Schizont, Trophozoite and Ring malaria stages. The layer thicknesses are then optimized and it is found that the proposed SPRE sensor can achieve a sensitivity of 278.378, 227.027 and 4 0 0 ∘ /RIU for Schizont, Trophozoite and Ring malaria stages with 30 nm (silver), 1 nm (STO), mono-sheet of graphene and 5 nm of the affinity layer. These findings demonstrate that the proposed method and structure can be used efficiently for biomedical applications. [ABSTRACT FROM AUTHOR]
Details
- Language :
- English
- ISSN :
- 02179849
- Volume :
- 37
- Issue :
- 36
- Database :
- Academic Search Index
- Journal :
- Modern Physics Letters B
- Publication Type :
- Academic Journal
- Accession number :
- 173940070
- Full Text :
- https://doi.org/10.1142/S0217984923501907