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Second and fourth (2D:4D) digit ratio in heroin and cannabis addicted patients.
- Source :
-
Journal of Ethnicity in Substance Abuse . Nov2023, p1-14. 14p. 1 Illustration, 4 Charts. - Publication Year :
- 2023
-
Abstract
- Abstract The etiology of addiction has not yet been fully elucidated. The ratio between the length of the second and fourth fingers (2D:4D ratio) has been linked with prenatal androgen concentrations, but also with addictive behvaiors. Aim: The present study aimed to evaluate the differences of 2D:4D ratio of individuals with cannabis and heroin addiction by examining them together with the control group. A total of sixty two male patients (33 opiate use disorder and 29 cannabis use disorder) with substance use disorder and the twenty-nine healthy controls were included in the present investigation. We obtained the lengths of 2D and 4D of the subjects by using sensitive calipers and calculated the 2D:4D. Heroin-addicted patients had lower 2D:4D ratio in in the right hand (significant difference between control group) (<italic>p</italic> < 0.001), there was no significant difference found between heroin-cannabis (<italic>p</italic> = 0.242) and control-cannabis 2D:4D ratios (<italic>p</italic> < 0.06). In the left hand, it was significant between the heroin-control groups (<italic>p</italic> < 0.037) and the cannabis-control groups (<italic>p</italic> < 0.023), while it was not significant between the heroin-cannabis groups (<italic>p</italic> = 1). In conclusion, we suggest that heroin-and cannabis addicted patients seem to have a lower ratio of 2D:4D compared to healthy control subjects. Our findings can be considered promising as to whether prenatal hormonal factors are important in the etiopathogenesis of addiction. [ABSTRACT FROM AUTHOR]
Details
- Language :
- English
- ISSN :
- 15332640
- Database :
- Academic Search Index
- Journal :
- Journal of Ethnicity in Substance Abuse
- Publication Type :
- Academic Journal
- Accession number :
- 173957772
- Full Text :
- https://doi.org/10.1080/15332640.2023.2278475