2017 至2022 年太原市HIV 抗体不确定 及后续随访阳转样本WB 条带及流行病学因素分析.

Objective: Explore characteristics of western blot band patterns and the epidemiological factors in cases with indeterminate HIV antibody and seroconversion with follow-up visit. Methods: Analyze western blot band patterns and the epidemiological factors on 790 cases with indeterminate HIV antibody and 71 follow-up seroconversion cases, in Taiyuan city from 2017 to 2022 years. Results: (1) Samples which have indeterminate HIV antibody, main come from hospitals, blood centers, and HIV voluntary counseling and testing (VCT) institutions, accounting for 84.47%. The positive seroconversion samples were mainly from hospitals and VCT institutions, accounting for 88.73%. In uncertain samples, the seroconversion rate of sexually transmitted diseases (STDs) clinic and VCT patients were higher than other sources, which was 50% and 25.49%. (2) The majority of uncertain samples and seroconversion samples were at the age of 20-40 years old, accounting for 53.8%. Among the uncertain samples, the rate of seroconversion samples at the age of 20-30 years old was the highest, accounting for 15.57%. (3) There was no significant difference in education level and gender among indeterminate samples, but the proportion of male seroconversion samples was much higher than that of female, and the rate of high educated population was relatively higher. (4) The majority of the indeterminate samples were married people, without high-risk behaviors, and employed people. The samples of positive conversion were mainly unmarried, divorced, widowed, spouses infected HIV, men who have sex with men (MSM), students, and unemployed people. (5) P24 and P17 were main bands and patterns in indeterminate samples, while P24 and P17 were the main bands in seroconversion samples. The patterns containing P24 or gP160 band were main and had the higher rate to seroconvert. Conclusion: Among the indeterminate HIV antibody samples, samples with characteristics of STD clinic, VCT, MSM, 20-30 years old, unmarried, unemployed and P24 or gP160 band were more likely to seroconvert. It is necessary to focus on the pepole who have above factors for prevention and control. It is important to follow up and test cases with above characteristics. [ABSTRACT FROM AUTHOR]