Non-coding RNAs: an emerging player in osteomyelitis.

Osteomyelitis is a debilitating bone infection primarily caused by Staphylococcus aureus. Despite advancements in surgery and chemotherapy, the treatment of osteomyelitis remains unsatisfactory, characterized by antibiotic resistance and recurrent relapses. Numerous studies have confirmed that non-coding RNAs could play an emerging role in regulating gene expression, as well as in the differentiation of osteoblasts and osteoclasts, along with bone formation. In this context, we provide an overview of current knowledge regarding the roles of non-coding RNAs in osteomyelitis and explore the potential therapeutic applications of these molecules in disease management, aiming to uncover novel diagnostic and treatment approaches. [ABSTRACT FROM AUTHOR]