Overcoming Challenges to Implementing New Evidence for Low-Dose Anticoagulant Use in Peripheral Artery Disease.

This document discusses the challenges and benefits of implementing low-dose anticoagulant use in patients with peripheral artery disease (PAD). The article highlights the prevalence and seriousness of PAD, as well as the underutilization of guideline-recommended therapies. The VOYAGER PAD and COMPASS trials have provided evidence supporting the use of low-dose anticoagulation in PAD patients, particularly those who have undergone endovascular revascularization procedures. The article emphasizes the need for further research, safety studies, and implementation efforts to ensure the effective use of low-dose anticoagulants in clinical practice. Additionally, barriers such as high drug prices and prescriber behavior are discussed, and potential interventions to increase anticoagulation use are suggested. [Extracted from the article]