Cobblestone‐like plaques on the cicatricial lower extremity resembling elephantiasis.

This article discusses a case study of a 32-year-old female who presented with cobblestone-like plaques on her lower extremity, resembling elephantiasis. The patient had previously undergone dermatoplasty for suspected elephantiasis, but the current lesions were found to be eccrine syringofibroadenoma (ESFA), a rare cutaneous adnexal neoplasm. The histopathological examination revealed anastomosing epithelial strands extending from the epidermis into the dermis, with ductal differentiation. The authors suggest that the ESFA in this case may be reactive to the scars, chronic inflammation, and lymphedema. The recommended treatment is complete excision, but unfortunately, the patient was lost to follow-up. The article also discusses the potential risk factors for skin tumors, such as cutaneous trauma and the role of cicatrization and chronic inflammation in tumorigenesis. [Extracted from the article]