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Intoxicación por cianuro posterior a infusión prolongada de Nitroprusiato de sodio: a propósito de un caso.

Authors :
Berrouet Mejía, Marie Claire
Castaño Vélez, Manuela
Zuluaga Gómez, Mateo
Source :
Medicina UPB. jul-dic2023, Vol. 42 Issue 2, p66-70. 5p.
Publication Year :
2023

Abstract

Sodium Nitroprusside has been approved since 1974 as a medication for hypertensive crises. However, there has been ongoing controversy regarding its potential toxicity. Cyanide toxicity is a rare complication of Sodium Nitroprusside, which can be challenging to diagnose in critically ill patients. Risk factors include prolonged infusions and high doses; hence it is suggested that the dose should not exceed 2 µg/kg/min. Here, we present the case of a 49-year-old patient who entered the emergency department after a cerebrovascular event and a hypertensive emergency that required Sodium Nitroprusside infusion, followed by signs and symptoms suggestive of toxicity. Neurological changes were predominant among these symptoms, and the patient was managed with sodium thiosulfate, resulting in a good response. The objective of this case report is to raise awareness among healthcare professionals about the need for appropriate use of Sodium Nitroprusside and the importance of suspecting toxicity in patients with risk factors. [ABSTRACT FROM AUTHOR]

Details

Language :
Spanish
ISSN :
01204874
Volume :
42
Issue :
2
Database :
Academic Search Index
Journal :
Medicina UPB
Publication Type :
Academic Journal
Accession number :
174486039
Full Text :
https://doi.org/10.18566/medupb.v42n2.a09