In reply to the Letter to the Editor regarding "Awake surgery for glioma resection during pregnancy: a systematic review".

The article is a response to a letter regarding a systematic review titled "Awake surgery for glioma resection during pregnancy." The authors address concerns raised about the lack of nuanced appraisal and familiarity in conducting and evaluating systematic reviews of case reports and case series. They explain the reasons for not registering their study in the PROSPERO registry and discuss the limitations of existing tools for assessing the risk of bias in case reports and case series. The authors also clarify the scope of their review and compare their findings with another recently published article on the same topic. They emphasize the need for careful interpretation of evidence from systematic reviews of case reports and case series and suggest that they serve as a base for achieving higher levels of evidence. [Extracted from the article]