Evaluation of endometrial pathology with transvaginal sonography (TVS) and pipelle sampling device in women with post-menopausal bleeding per vagina.

Background: Bleeding per vagina following established menopause is called Post-Menopausal bleeding; even without amenorrhea or irregularity menstruation continuing after age of 55 years should be investigated. The objective of this study was to study the correlation of findings in TVS and Pipelle sampling biopsy in diagnosis of endometrial pathology. Methods: The present Prospective Observational study was conducted in the Department of Obstetrics and Gynaecology, Department of Pathology, and Department of Radiology, Calcutta National Medical College and Hospital, Kolkata, West Bengal, India between March 2022 to February 2023. Outdoor patients in postmenopausal age group presenting with Post-menopausal bleeding per vagina during same period after fulfilling the inclusion criteria were included in the study. Statistical data were analysed by using Microsoft Excel and SPSS V.20 software. Results: We found that, out of 50 patients, 26(52%) patients were <50 years of age, 22(44.0%) patients were 51-60 years of age, 2(4.0%) patients were >61 years of age. The mean age of patients was 51.7600 years. We observed 32(64.0%) patients had 1-3 months duration of post-menopausal bleeding and 18(36.0%) patients had 4-6 months duration of PMB. We found that, 46(92.0%) patients had Successful entry of Pipelle's into endometrial cavity which was statistically significant. Our study showed that, 09(100.0%) patients were with detected endometrial carcinoma and atypical endometrial hyperplasia in TVS and was statistically significant. About 07(87.78%) patients were detected with endometrial carcinoma and atypical complex endometrial hyperplasia in Pipelle's biopsy which was statistically significant. Conclusion: The clinical approach to post-menopausal bleeding requires prompt and efficient evaluation to exclude or diagnose endometrial carcinoma and endometrial hyperplasia. [ABSTRACT FROM AUTHOR]