Cyclophosphamide/rituximab/steroids: Treatment failure and acute promyelocytic leukaemia.

Author InformationAn event is serious (based on the ICH definition) when the patient outcome is:• * death * life-threatening * hospitalisation * disability * congenital anomaly * other medically important eventA 52-year-old woman exhibited treatment failure during treatment with rituximab and unspecified steroids and developed acute promyelocytic leukaemia (APL) during treatment with cyclophosphamide for granulomatosis with polyangiitis [GPA; not all dosages stated; routes and duration of treatment to reaction onset not stated]. [Extracted from the article]