双重细菌性肝脓肿 7 例病原学和临床特点.

Objective To explore the pathogenic and clinical characteristics of 7 cases of double bacterial hepatic abscess. Methods The clinical data of 7 cases of double bacterial hepatic abscess treated in this hospital from January 2015 to December 2021 were analyzed retrospectively. The bacterial spectrum, clinical manifestations and complications were analyzed, and the clinical characteristics of double mixed bacterial hepatic abscess were summarized. Results In 7 cases of double mixed bacterial hepatic abscess, the age was 22.078.0 years old, the mean age was (58.9±17.7) years old, the mean hospital stay time was (15.6±10.9) d. Six cases (85.7%) were complicated with underlying disease and previous surgical history. Fever (71.4%) and abdominal pain (57.1%) were the main symptoms. Pneumonia and pleural effusion were the main complications. The mean diameter of hepatic abscess was (6.1±3.2) cm, and all patients were cured by percutaneous puncture and drainage of hepatic abscess combined with antibiotics for anti-infection treatment. All patients had varied degree of liver function injury. The main pathogenic bacteria were Klebsiella pneumoniae and Escherichia coli. The proportions of cephalosporin and quinolone antibiotic resistance all were 57.1% (4/7), and carbopenem antibiotic resistance proportion was 28.6% (2/7). Conclusion Double mixed hepatic abscess usually occurs in the elderly patients with complicating underlying disease and previous surgical history. Klebsiella pneumoniae and Escherichia coli are main pathogenic bacteria, moreover which are easy to have drug resistance. [ABSTRACT FROM AUTHOR]