To Assess Symptomatic Profile in Patients with Chronic Rhinosinusitis Before and After Functional Endoscopic Sinus Surgery by Sinonasal Outcome Test-22.

Purpose: This study designed to compare the symptomatic profile of diagnosed patients of chronic rhinosinusitis (CRS) before and after functional endoscopic sinus surgery (FESS) by a 22-item Sino-Nasal Outcome Test (SNOT-22) questionnaire. Study design: Observational mixed-design study. Materials and Methods: It is an observational mixed-design study conducted in the department of ENT, Dr. S.N. Medical College, jodhpur from February 2021 to September 2022. A total of 50 patients were included in our study who underwent functional endoscopic sinus surgery. Their symptomatic improvement based on the SNOT-22 score, was compared before and after surgery. Follow-up of patients was done at 1 month and 3 months by SNOT-22 score. Results: A total of 50 patients were included in our study, 42 patients were telephonically communicated and followed up, and 8 patients were lost to follow-up, so 42 patients' data were analyzed. The mean age was 35.42 years. The mean total SNOT-22 score preoperatively was 45.64, postoperatively at 1 month was 6.57, and postoperatively at 3 months was 2.52. The mean difference between preoperative and postoperative scores was 43.11. This shows a significant reduction in postoperative scores as well as improvement in symptoms at the end of 3 months. Conclusion: Preoperatively 64.24% of the patients had a grand total score of 20–50 (showing a moderate impact on quality of life) and 35.71% of patients having a score > 50 (showing a severe impact on quality of life). Observations in our study suggest that Functional endoscopic sinus surgery provides a significant symptom-specific improvement as well as a significant quality of life improvement in patients with chronic rhinosinusitis with or without polyposis. SNOT-22 questionnaire provides an ideal way to understand and grade the disease severity preoperatively and compare the symptomatic improvement after functional endoscopic sinus surgery in patients with chronic rhinosinusitis. [ABSTRACT FROM AUTHOR]