Synthesis of β‐Hydroxysulfides via Multi‐Component Cascade Hydroxysulfenylation of Styrenes with NH4SCN and Water under Transition‐metal‐free Conditions.

Transition‐mental‐free multi‐component hydroxysulfenylation of styrenes with NH4SCN and water to from β‐hydroxysulfides is established. The reaction mechanism proceeded via a domino reaction after a radical addition to 2‐phenylimidazo[1,2‐a]pyridines. This approach features a wide substrate scope and functional group compatibility, providing 34 compounds in acceptable yields. [ABSTRACT FROM AUTHOR]