Multiple drugs: Lack of efficacy and cytokine release syndrome.

Author InformationAn event is serious (based on the ICH definition) when the patient outcome is:• * death * life-threatening * hospitalisation * disability * congenital anomaly * other medically important eventIn a study, et al. 57-year-old man was described, who exhibited a lack of efficacy during treatment with folinic acid, fluorouracil, oxaliplatin, nivolumab, irinotecan and ramucirumab for metastatic gastric cancer. Subsequently, he developed cytokine release syndrome (CRS) during treatment with CT-041 for metastatic gastric cancer [not all routes and dosages stated; duration of treatment to reaction onset not stated]. [Extracted from the article]