СРІБЛОВМІСНІ НАНОМАТЕРІАЛИ: ОТРИМАННЯ, МОРФОЛОГІЯ, АНТИМІКРОБНА ТА ПРОТИВІРУСНА АКТИВНІСТЬ.

Infectious diseases caused by viruses and microorganisms continue to be one of the biggest health problems worldwide, despite the rapid progress in the creation of drugs and the development of pharmaceutical technologies. Th e risk of complications and the spread of infections in society remains high. Scientifi c research and the fi ght against viral infections, in particular with a large group of respiratory diseases caused by viruses, such as infl uenza viruses, parainfl uenza viruses, respiratory sensitivities, adenoviruses, rhinoviruses, coronaviruses, etc., occupy an important place in modern medicine. Due to the nature, characteristics and biological and physical properties of viruses, the issues of combating them are very acute. Microorganisms resistant to many antimicrobial agents are also developing (Staphylococcus aureus, Escherichia coli, Pseudomonas aeruginosa, Candida albicans, etc.). Th erefore, today there is an urgent need for new materials with a higher antiviral and bactericidal eff ect, less toxicity for humans and the environment (ecology, medicine and food industry). Silver-containing biomaterials in various forms (powders, fi lms, solutions, products formed by 3D printing technology) with eff ective antimicrobial and antiviral eff ects have been developed. Th e materials are made on the basis of polyelectrolyte complexes of polysaccharides (pectin – chitosan, pectin – cationic starch, carboxymethylcellulose – cationic β-cyclodextrin, anionic starch – cationic starch) and polylactide biopolymer. Silver nanoparticles in the composition of composites were formed in environmentally friendly ways: by reduction silver ions with extracts of natural substances (green tea, mint, propolis, pectin), by methods of thermochemical reduction or cathodic sputtering of silver nanoparticles from silver foil onto the surface of the fi lm. Th e structure, morphology, obtained materials and their antimicrobial, antiviral and cytotoxic properties were studied. Th e relationship between the structure and morphology and the protective properties of the obtained materials was studied. [ABSTRACT FROM AUTHOR]