Drug Cues Trigger Corticolimbic Hyperreactivity in Heroin Users.

The article discusses a neuroimaging study revealing heightened corticolimbic reactivity in heroin-addicted individuals to drug-related cues compared to healthy controls. The study explores two addiction theories, iRISA and incentive sensitization, suggesting that increased salience and motivational "wanting" for drugs contribute to limbic hyperreactivity. Topics include neural hyperreactivity patterns, cognitive regulation attempts, and implications for addiction treatment strategies.