Back to Search
Start Over
Neutrophil/Lymphocyte Ratio and Platelet/Lymphocyte Ratio and Their Relationship with Nutritional Status and Quality of Life of Hospitalized Women with Breast Cancer.
- Source :
-
Nutrition & Cancer . 2024, Vol. 76 Issue 3, p296-304. 9p. - Publication Year :
- 2024
-
Abstract
- Blood cell biomarkers, such as the neutrophil-lymphocyte ratio (NLR) and the platelet-lymphocyte ratio (PLR), have been recently used as prognostic markers in tumors. In this study, we investigated the association between NLR and PLR with sociodemographic, clinical, anthropometric, and quality of life factors of hospitalized women with non-metastatic breast cancer. A cross-sectional observational study was conducted at a reference center for oncological treatment in Southeast Brazil. Female participants aged over 18 years, with a histopathological diagnosis of stage I, II or III breast cancer, in any phase of antineoplastic treatment, were included. Our study revealed a high risk for participants, with high mean values of NLR and PLR, indicating low antitumor activity and worse prognosis. The binary logistic regression model showed that there was a significant association of the NLR marker and marital status (OR = 3.1; 95%CI = 1.06-8.57; p = 0.03) and, in relation to PLR, a trend was shown for a higher chance in women of black ethnicity to have increased PLR compared to white women (OR = 4.13; 95%CI = 0.96-17.70; p = 0.05). However, the inflammatory markers (NLR and PLR) did not show any significant association with nutritional factors. NLR and PLR are inflammatory biomarkers that can be easily obtained and measured in clinical practice. [ABSTRACT FROM AUTHOR]
- Subjects :
- *BREAST cancer prognosis
*BREAST tumor diagnosis
*THERAPEUTIC use of antineoplastic agents
*BIOMARKERS
*HOSPITAL patients
*PLATELET lymphocyte ratio
*SCIENTIFIC observation
*CONFIDENCE intervals
*ANTHROPOMETRY
*CROSS-sectional method
*INFLAMMATION
*METASTASIS
*RACE
*NEUTROPHIL lymphocyte ratio
*QUALITY of life
*DESCRIPTIVE statistics
*RESEARCH funding
*SOCIODEMOGRAPHIC factors
*LOGISTIC regression analysis
*MARITAL status
*ODDS ratio
*DATA analysis software
*BREAST tumors
*NUTRITIONAL status
*WOMEN'S health
Subjects
Details
- Language :
- English
- ISSN :
- 01635581
- Volume :
- 76
- Issue :
- 3
- Database :
- Academic Search Index
- Journal :
- Nutrition & Cancer
- Publication Type :
- Academic Journal
- Accession number :
- 175195010
- Full Text :
- https://doi.org/10.1080/01635581.2024.2304689