Adalimumab/doxycycline/golimumab: Blepharitis and lack of efficacy.

A 15-year-old boy with Crohn's disease developed blepharitis while being treated with adalimumab and golimumab. He also experienced lack of efficacy when treated with doxycycline for the blepharitis. The boy's symptoms improved when he was switched to amoxicillin/clavulanic acid and later ustekinumab. His digestive, rheumatological, and dermatological symptoms were controlled, and he was able to taper off prednisone. [Extracted from the article]