Advances in Research on Pig Salivary Analytes: A Window to Reveal Pig Health and Physiological Status.

Simple Summary: The analysis of pig saliva, which is easily available and rich in bioactive ingredients, has been widely studied, showing potential in disease diagnosis and treatment for pig production management. Studies have shown that porcine saliva analytes have important application potential in disease detection and can be used as disease biomarkers and therapeutic monitoring indicators, as well as for prognostic evaluation. Through the changes in specific proteins, metabolites, and microbial composition in porcine saliva, porcine saliva analytes can provide a new strategy for early diagnosis, prognosis assessment, and treatment of diseases. This review introduces the composition and function of analytes in porcine saliva. Different analytes in porcine saliva are widely employed in diseases. As an indicator of pig health, saliva can be used as a noninvasive sample for disease detection and monitoring. Saliva is an important exocrine fluid that is easy to collect and is a complex mixture of proteins and other molecules from multiple sources from which considerable biological information can be mined. Pig saliva, as an easily available biological liquid rich in bioactive ingredients, is rich in nucleic acid analytes, such as eggs, enzymes, amino acids, sugars, etc. The expression levels of these components in different diseases have received extensive attention, and the analysis of specific proteins, metabolites, and biological compositions in pig saliva has become a new direction for disease diagnosis and treatment. The study of the changes in analytes in pig saliva can provide a new strategy for early diagnosis, prognosis assessment, and treatment of diseases. In this paper, the detection methods and research progress of porcine salivary analytes are reviewed, the application and research progress of porcine salivary analytes in diseases are discussed, and the future application prospect is presented. [ABSTRACT FROM AUTHOR]